MicrobiologyPLoS neglected tropical diseasesPeer-reviewed
Impact of Inactivation Methods on Biosafety and Antigen Reactivity of Brucella melitensis from the Perspective of Astral-DIA Proteomics Based on Antibody Immunoprecipitation Mass Spectrometry
Yijian Liu, Jiazhen Ge, Guodong Song…·Fuying Zheng
This study evaluates inactivation methods for Brucella melitensis using Astral-DIA proteomics, finding that heat and formaldehyde affect antigenicity and protein expression differently across strains.
DOI 10.1371/journal.pntd.0013397