BiochemistrybioRxivPreprint
Selective suppression and biasing of chemokine receptors CCR9 and ACKR4 through targeting CCL25 with de novo miniproteins
Bas De Boer, Thomas D Lamme, Karlijn Verdwaald…·Christopher T. Schafer
The paper designs miniproteins that selectively block or bias chemokine receptor signaling by targeting CCL25, demonstrating their ability to suppress CCR9 and modulate ACKR4 responses.
DOI 10.64898/2026.01.23.701245