Nick Steele

In 50 trauma-exposed veterans, thalamic hypoactivity to near virtual-reality threats tracked both PTSD and MDD severity, while amygdala hyperactivity to far threats tracked only PTSD severity.

IBMMA improves neuroimaging analysis by handling missing data and large datasets, revealing new brain region findings overlooked by traditional methods.

The paper examines thalamic volume differences in trauma-exposed individuals with PTSD, MDD, and controls, finding specific volume reductions and associations with symptom severity and childhood trauma.