Author

Kaja S. Menge

Medizinische Hochschule HannoverORCID 0009-0004-2711-1621Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anna Melchert· 1 shared Colin DavenportiD· 1 shared Gudrun GöhringiD· 1 shared Ina GruhiD· 1 shared Jonas Gruber· 1 shared Lutz Wiehlmann· 1 shared Maike KosankeiD· 1 shared Maike Sievert· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Anna Melchert

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1 paper

Recent·Most cited

GenomicsStem Cell ReportsPeer-reviewedSep 23, 2021

iPSC culture expansion selects against putatively actionable mutations in the mitochondrial genome

Maike Kosanke, Colin Davenport, Mónika Szepes…·Ulrich Martin

The paper analyzes mtDNA variants in iPSCs and finds that culture expansion selects against harmful mitochondrial mutations, while reprogramming and differentiation do not significantly alter mtDNA heteroplasmy.

16 citations

humanwhole-genome sequencing

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