Molecular BiologybioRxivPreprint
Ferroptotic vulnerability of post-meiotic germ cells skews sex chromosome ratios in aged testis
Jasper Germeraad, Takako Kikkawa, Junya Ito…·Noriko Osumi
This study shows that aging increases ferroptotic vulnerability in round spermatids, leading to a Y-chromosome skew in sperm, which can be modulated by vitamin E.
DOI 10.1101/2024.10.21.619554