A JNK-interacting protein 1 acts across the midline to mediate synaptic localization of the SARM1 calcium-signaling scaffold protein for asymmetric neuronal fate choice
Yi‐Wen Hsieh, Shengyao Yuan, Jun Yang, Cesar Siete, Chiou‐Fen Chuang
This study identifies JIP-1 as a mediator of synaptic TIR-1 localization in C. elegans AWC neurons, promoting asymmetric subtype specification through non-cell autonomous signaling.
bioRxiv · May 5, 2026 · PreprintDevelopmental Biology