Author

Tze Yee Lim

Imperial College LondonORCID 0009-0004-4594-6382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Catherine M. TromaniD· 1 shared Min Jung KwuniD· 1 shared Nicholas J. CroucheriD· 1 shared Samuel HorsfieldiD· 1 shared Stephen D. BentleyiD· 1 shared

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2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Catherine M. TromanORCID

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1 paper

Recent·Most cited

GenomicsPLoS PathogensPeer-reviewedAug 14, 2025

Pore-C sequencing identifies episome-driven chromosome conformation perturbations differentiating pneumococcal epigenetic variants

Tze Yee Lim, Samuel Horsfield, Catherine M. Troman…·Nicholas J. Croucher

The paper uses Hi-C and Pore-C sequencing to compare chromosomal conformation in pneumococcal variants, finding that episomal elements drive differential contact patterns through stochastic replication and excision.

1 citation

bacteria (other)Hi-C

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