Dong‐Guk Shin

OFC-SV is a web portal that interprets structural variants in genomic data from African and Asian cohorts with non-syndromic orofacial clefts, identifying 41 novel SV genes and their regulatory impacts.

The paper identifies structural variants in the DOT1L locus associated with non-syndromic orofacial clefts in children of African and Asian ancestry, supporting an oligogenic model for cleft lip/palate susceptibility.

The paper introduces vSPACE, a method to create virtual spatial representations of single-cell RNA sequencing data from human articular cartilage, revealing consistent zonal patterns across donors.

CGCom uses a graph neural network to infer cell-cell communication from spatial transcriptomics data, showing improved accuracy over existing methods.