Author

Néstor R. Aznar

ORCID 0009-0004-5566-3706Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:experimental assay· 1

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Irene Beatriz LarripaiD· 1 shared Marcela González‐Cid· 1 shared Marcelo de Campos Nebel· 1 shared Maria Camila GossoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperMolecular Biology

Irene Beatriz LarripaORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintMay 29, 2026

TDP1 drives MRE11-dependent and independent end resection during replication stress by TOP2 poisons

Néstor R. Aznar, Maria Camila Gosso, Irene Beatriz Larripa…·Marcelo de Campos Nebel

This study shows TDP1 and MRE11 work together to remove TOP2cc lesions during replication stress, with TDP1 promoting DNA end resection through both MRE11-dependent and -independent pathways.

DOI 10.64898/2026.05.29.728668

experimental assay

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