BiochemistryJournal of Biological ChemistryPeer-reviewed
Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain
Anthony Castro, Alfredo Ruiz-Rivera, Chad C Moorman…·Jason R. Burke
This study analyzes how cancer-associated missense variants in Rb's pocket domain affect its binding and stability using biophysical assays and crystallography.
2 citations