Author

Chad C Moorman

California State University, San BernardinoORCID 0000-0002-2592-9735Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Alfredo Ruiz-RiveraiD· 2 shared Emma R Wolf-SaxoniD· 2 shared Hailey N MimsiD· 2 shared Jason R. BurkeiD· 2 shared Matthew A RangeliD· 2 shared Vanessa I. Vasquez MezaiD· 2 shared Anthony CastroiD· 1 shared Estela VillarrealiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

Alfredo Ruiz-RiveraORCID

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Author profile →

2 papers

Recent·Most cited

Snapshots from the Catalytic Landscape of Chalcone Isomerase

Jason R. Burke, Matthew A Rangel, Vanessa I. Vasquez Meza, Hailey N Mims, Thomas O Darko, Kelwyn Matthew Ixcoy, Alfredo Ruiz-Rivera, Jason Zhang, Emma R Wolf-Saxon, Chad C Moorman

This study investigates the dynamic conformational changes of chalcone isomerase using structural and biochemical methods, revealing how flexibility in the active site facilitates substrate rearrangements during catalysis.

bioRxiv · Sep 3, 2026 · PreprintBiochemistry

Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain

Anthony Castro, Alfredo Ruiz-Rivera, Chad C Moorman, Emma R Wolf-Saxon, Hailey N Mims, Vanessa I. Vasquez Meza, Matthew A Rangel, Marcos M Loera, Ian C. Bond, Seth B Buchanan, Estela Villarreal, Sarvind Mani Tripathi, Seth M. Rubin, Jason R. Burke

This study analyzes how cancer-associated missense variants in Rb's pocket domain affect its binding and stability using biophysical assays and crystallography.

Journal of Biological Chemistry · Feb 10, 2025Peer-reviewedBiochemistry