Afredo Ruiz-Rivera

This study investigates the dynamic conformational changes of chalcone isomerase using structural and biochemical methods, revealing how flexibility in the active site facilitates substrate rearrangements during catalysis.

This paper identifies a β-strand complementation mechanism used by PilC/PilY1 proteins to license type IV filament assembly across diverse systems.

This paper describes a method to express and purify soluble type IV minor pilins from E. coli and identifies a heterodimeric interaction between PilI and PilJ in Neisseria gonorrhoeae.

This study analyzes how cancer-associated missense variants in Rb's pocket domain affect its binding and stability using biophysical assays and crystallography.