NeurosciencebioRxivPreprint
The interaction between aging and DNA damage influences the accumulation of APP in Alzheimer's disease
Eliana Brenner, Gnanesh Gutta, Fiona Stauffer…·Fulin Ma
The paper shows that DNA damage increases with age and correlates with higher APP levels in Alzheimer's disease, suggesting DNA damage drives APP accumulation.
DOI 10.1101/2025.09.07.674780