Structural basis of K+/H+ antiport in YcgO and its inhibition by unphosphorylated PtsN
Ayushi Srivastava, Arunabh Athreya, Yogesh Patidar, Vijeta Singh, Abhijit A. Sardesai, Aravind Penmatsa
This study determines the structure of YcgO, an E. coli K+/H+ antiporter, and shows how unphosphorylated PtsN inhibits its activity through interactions with cytosolic domains.
bioRxiv · Aug 18, 2026 · PreprintBiochemistry