Amélia Nicot

This study shows that cocaine abstinence increases enkephalin in D2-MSNs, reducing GABA release to VP neurons and promoting cocaine seeking.

The paper tests if striatal dynorphin-enkephalin balance affects cocaine avoidance in mice, finding no significant strain differences or enkephalin necessity.

The paper investigates the relationship between striatal opioid peptides and cocaine-induced conditioned place avoidance in mice, finding that low dynorphin levels correlate with increased avoidance.