Yancheng Du

Computational Design Strategies for Nanoscale 3D Auxetic Metastructures from DNA

This study develops design strategies for 3D auxetic metastructures made from DNA origami, showing how DNA bundle rigidity and joint mechanics influence auxetic behavior and deformation energetics.

Programmable assembly of higher-order DNA nanostructures from microbial ssDNA staple libraries

This paper develops a biological nanomanufacturing platform in E. coli to produce programmable ssDNA staples for DNA nanotechnology, achieving high-fidelity synthesis and self-assembly of complex structures.

A Nanoscale Jitterbug Transformer from DNA

This paper designs a DNA-based nanoscale Jitterbug transformer that reconfigures its structure in response to chemical and optical signals, maintaining a Poissons ratio of -1.

Realizing Mechanical Frustration at the Nanoscale Using DNA Origami

This paper uses DNA origami to create a nanoscale metastructure that can switch between frustrated and non-frustrated mechanical states, with distinct free energy profiles.

Programmable Aggregation of Artificial Cells with DNA Signals

This paper demonstrates programmable aggregation of synthetic cells using DNA signals, showing controlled assembly and disassembly of artificial cells.