Human mitochondrial RNA polymerase structures reveal transcription start-site and slippage mechanism
Jiayu Shen, Quinten Goovaerts, Yogeeshwar Ajjugal, Brent De Wijngaert, Kalyan Das, Smita S. Patel
The paper presents cryo-EM structures of human mitochondrial transcription initiation complexes, revealing mechanisms of start-site selection and slippage synthesis.
Molecular Cell · Dec 2, 2024Peer-reviewedBiochemistry