Mutations in Hsp40 co-chaperone change the unique canonical inter-domain interactions stimulating LGMDD1 myopathy
Ankan Kumar Bhadra, Geetika Aggarwal, Mahapatra Anshuman Jaysingh, Daniel C. Chen, Jil Daw, Conrad Chris Weihl, Heather L. True
The paper investigates how mutations in the J-domain of DNAJB6 affect chaperone function and inter-domain interactions, providing mechanistic insights into LGMDD1 myopathy.
Journal of Biological Chemistry · Nov 17, 2025Peer-reviewedBiochemistry