Author
Washington University in St. LouisORCID 0000-0002-8679-0984Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Geetika Aggarwal, Subhashis Banerjee, Ankan Kumar Bhadra…·Andrew Huy Nguyen
This study shows that progranulin deficiency increases NLRP3 inflammasome activity via cathepsin B, leading to neuroinflammation, and demonstrates that ASO treatment can reverse this effect in GRN-deficient cells.
Ankan Kumar Bhadra, Geetika Aggarwal, Mahapatra Anshuman Jaysingh…·Heather L. True
The paper investigates how mutations in the J-domain of DNAJB6 affect chaperone function and inter-domain interactions, providing mechanistic insights into LGMDD1 myopathy.
Leeran B. Dublin-Ryan, Ankan Kumar Bhadra, Heather L. True
This study shows that disrupting the NAC reduces polyglutamine aggregation and toxicity in cells.
Conrad Chris Weihl, Ana Töpf, Rocío Bengoechea…·Volker W. Straub
The paper identifies DNAJB4 loss of function variants causing a myopathy with early respiratory failure through exome sequencing and functional studies.