Author

Daniel Kaschta

Christian-Albrechts-Universität zu KielORCID 0009-0004-8128-5024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Almuth CaliebeiD· 2 shared Caroline Utermann-ThüsingiD· 2 shared Inga NageliD· 2 shared Inga Vater· 2 shared Malte SpielmanniD· 2 shared Vincent Arriens· 2 shared Alexander Erich VolkiD· 1 shared Alexander Maximilian MünchauiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Almuth CaliebeORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 19, 2026

AUTOMATED VERSUS MANUAL REANALYSIS IN RARE DISEASE GENOMICS

Daniel Kaschta, Vincent Arriens, Simon Mueller…·Malte Spielmann

The paper compares automated and manual reanalysis of rare disease genome sequencing data, finding automated methods achieve similar results with less effort.

DOI 10.64898/2026.05.16.26352295

humanwhole-exome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicineGenome MedicinePeer-reviewedSep 17, 2025

Evaluating Genome Sequencing Strategies: Trio, Singleton, and Standard Testing in Rare Disease Diagnosis

Daniel Kaschta, Christina Post, Franziska Gaass…·Malte Spielmann

This study compares trio, singleton, and standard genome sequencing in rare disease diagnosis, finding trio sequencing has the highest diagnostic yield.

10 citationstop 3%

humanwhole-genome sequencing

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