Molecular BiologybioRxivPreprint
Redistribution of sidechain-sidechain interactions govern ligand-specific binding affinity changes in missense Shank1 PDZ mutants
Anna Sánta, Zsófia E. Kálmán, Eszter Nagy‐Kanta…·Bálint Ferenc Péterfia
The paper investigates how missense mutations in Shank1 PDZ domain affect ligand-specific binding affinity through dynamic interactions.
DOI 10.1101/2025.07.03.662971