Bálint Ferenc Péterfia

The paper investigates how two autism-associated mutations in the Homer1 EVH1 domain affect its internal dynamics and binding properties using experimental and computational methods.

The paper shows that a hexameric complex of GKAP and LC8 proteins has constrained stoichiometry with retained flexibility in the linker region.

The paper investigates how missense mutations in Shank1 PDZ domain affect ligand-specific binding affinity through dynamic interactions.

This study presents an atomistic model of full-length Homer1 tetramer and NMR structure of its EVH1 domain, revealing ligand-induced conformational changes and dynamic regions in the coiled coil.

The paper analyzes the structural features of postsynaptic proteins to show that their combination of ordered and disordered regions enables diverse interactions crucial for learning and memory.