Author
University of California, Los AngelesORCID 0009-0004-8455-1308Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Moonseong Jeong, Zhengtong Liu, Jiayi Ni…·Sriram Sankararaman
SUMMIT improves heritability and genetic correlation estimation across diverse ancestries using LD scores and GWAS summary statistics, showing better accuracy in non-European populations.
Yash Patel, Chenghao Zhu, Takafumi N. Yamaguchi…·Paul Christopher Boutros
Metapipeline-DNA automates comprehensive analysis of DNA sequencing data from raw reads to visualization, supporting germline and somatic genomic features.
Zhengtong Liu, Boyang Fu, Moonseong Jeong…·Sriram Sankararaman
This paper introduces FLEX, a method for estimating gene-level heritability from whole-exome sequencing data, showing rare coding variants contribute significantly to complex trait heritability.
Boyang Fu, Prateek Anand, Aakarsh Anand…·Sriram Sankararaman
The paper introduces QuadKAST, a scalable algorithm for detecting epistasis in complex traits, and identifies 32 trait-gene pairs with significant quadratic effects in UK Biobank data.
Boyang Fu, Ali Pazokitoroudi, Albert Xue…·Sriram Sankararaman
The paper tests for polygenic epistasis in biobank-scale data and finds 16 trait-loci pairs with strong evidence of interaction effects.
Prateek Anand, Anji Liu, Meihua Dang…·Sriram Sankararaman
This paper introduces GPC, a deep generative model for genetic variation data that improves imputation accuracy and privacy preservation compared to existing methods.