Author

Nicholas Tolli

NoblisORCID 0009-0004-8648-5789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Bradley W. AbramsoniD· 3 shared Daniel Antonio NegróniD· 3 shared Katharine JenningsiD· 3 shared Bryan D. NecciaiiD· 2 shared David A. Ashford· 2 shared Gabrielle Melton· 2 shared Shanmuga SozhamannaniD· 2 shared Stephanie L. GuertiniD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBioinformatics

Bradley W. AbramsonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioinformaticsScientific ReportsPeer-reviewedSep 15, 2026

Multi-feature Classification to Improve Colorimetric Loop-Mediated Isothermal Amplification Fidelity

Gabrielle Melton, Daniel Antonio Negrón, Kelsey Hauser…·Bradley W. Abramson

The paper develops a machine learning model to improve LAMP assay design by identifying key thermodynamic features from primer sets, achieving high classification accuracy.

DOI 10.1038/s41598-026-70510-9

machine learning (classical)benchmarking

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJun 29, 2024

Loop-Mediated Isothermal Amplification Assays for the Detection of Antimicrobial Resistance Elements in Vibrio cholerae

Daniel Antonio Negrón, Shipra Trivedi, Nicholas Tolli…·Bradley W. Abramson

The paper develops an algorithm for designing LAMP assays and a computer vision tool for analyzing colorimetric outputs to detect antimicrobial resistance in Vibrio cholerae.

DOI 10.1101/2024.06.29.601342

bacteria (other)statistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 24, 2023

Clade-Specific MPXV PCR Assays

Daniel Antonio Negrón, Nicholas Tolli, Stephanie L. Guertin…·David A. Ashford

The paper presents clade-specific PCR assays for mpox virus detection, improving accuracy and enabling clade identification during outbreaks.

2 citations

experimental assay

𝕏 PostBluesky