Api5-FGF2 regulates the transformation of breast epithelial cells via PDK1/Akt and Ras/MAPK/ERK signalling
This study shows that Api5 overexpression increases FGF2 levels and activates PDK1/Akt and Ras/MAPK/ERK pathways, leading to breast epithelial cell transformation.
bioRxiv · Feb 18, 2026 · PreprintCancer Biology