Reln haploinsufficiency enhances fentanyl-induced locomotion and striatal activity without affecting opioid reinforcement and relapse-like behavior
Carl G. Litif, Avraham M. Libster, Shane Desfor, Tanieng Huang, Leanne Liaw, Annika Cheng, Francesca Telese
This study shows that Reln haploinsufficiency increases fentanyl-induced locomotion and striatal activity but does not affect opioid reinforcement or relapse-like behavior.
bioRxiv · Mar 18, 2026 · PreprintNeuroscience