LOXL2 alleviates post-traumatic knee osteoarthritis and pain
Faiza Ali, Rajnikant Dilip Raut, Chumki Choudhury, Amit Kumar Chakraborty, Cheyleann Del Valle-Ponce De Leon, Pushkar Mehra, Manish V. Bais
This study shows that LOXL2 deletion in mice worsens post-traumatic knee osteoarthritis and pain, resembling human OA, and that LOXL2 injection improves joint function and reduces pain.
Journal of Orthopaedic Translation · Nov 1, 2025Peer-reviewedMolecular Biology