Transient ATM inhibition enhances knock-in efficiency in hematopoietic stem cells by attenuating the DNA damage response
Munkh‐Erdene Natsagdorj, Hiromasa Hara, Kohei Iida, Yuji Kashiwakura, Tsukasa Ohmori, Yutaka Hanazono, Fumio Nakahara
This study shows that transient ATM inhibition improves knock-in efficiency in mouse hematopoietic stem cells by reducing DNA damage response and apoptosis.
bioRxiv · Sep 3, 2025 · PreprintCell Biology