Author
Icahn School of Medicine at Mount SinaiORCID 0009-0004-9712-6378Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Elisa Navarro, Anastasia G. Efthymiou, Daniele Mattei…·Towfique Raj
This study shows the G2019S LRRK2 mutation alters transcriptomes of myeloid cells under proinflammatory conditions, affecting lipid metabolism and phagocytic function.
Winston H. Dredge, Kailash BP, Aline Réal…·Towfique Raj
The paper identifies 38,731 edQTLs in 3,554 genes through a meta-analysis of A-to-I RNA editing in the human brain and links 24 GWAS loci for neurological disorders to edQTLs.
Aline Réal, Kailash BP, Winston H. Dredge…·David A. Knowles
The paper maps genetic effects on splicing in 10,725 brain samples, identifying 68,358 cis-sQTLs and 97 loci where splicing mediates neurological disease risk.
Gijsje J. L. Snijders, Kátia de Paiva Lopes, Marjolein A. M. Sneeboer…·Lot D. de Witte
The paper characterizes the human microglia responsome by analyzing gene expression in microglia exposed to various stimuli, identifying distinct responses and genetic interactions relevant to disease.
Jack Humphrey, Erica Brophy, Roman Kosoy…·Towfique Raj
The paper presents a long-read RNA-seq atlas of microglia isoforms, identifying novel isoforms and their associations with genetic risk loci in Alzheimer's and Parkinson's disease.