The paper develops a thalamocortical model to study how neuronal composition and connectivity affect allopregnanolone's effectiveness in resolving seizures in childhood absence epilepsy.

1 citation

deep learningexperimental assay

𝕏 PostBluesky

NeuroscienceJournal of Computational NeurosciencePeer-reviewedDec 21, 2024

Modelling the Effect of Allopregnanolone on the Resolution of Spike-Wave Discharges

Maliha Ahmed, Sue Ann Campbell

This study models how allopregnanolone affects spike-wave discharges in a thalamocortical circuit, showing region-specific amelioration in the thalamus.

3 citations

statistical model

𝕏 PostBluesky