Author

Nikolaos Komianos

ORCID 0009-0005-0717-8340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Pranadarth PrakashiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 17, 2026

Retention, not flux: endpoint confounding caps computational prediction of peptide skin penetration, with a delivery-aware reframing

Nikolaos Komianos, Pranadarth Prakash

The paper argues that predicting peptide skin penetration is limited by endpoint confounding and proposes a delivery-aware reframing to improve computational predictions.

DOI 10.64898/2026.06.25.734657

proteomicsstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 14, 2026

Constrained Evolutionary Design of Matrixyl Analogs: Balancing Permeability and Functional Preservation Through Computational Optimization

Nikolaos Komianos, Pranadarth Prakash

The paper designs Matrixyl analogs using computational optimization to balance permeability and functional preservation, identifying three sequences for experimental validation.

DOI 10.64898/2026.05.12.724473

statistical modeldrug response / drug discovery

𝕏 PostBluesky