Irene Bonafonte-Pardàs

DextraDemixer improves identification of antigen-specific T cells from pMHC multimer data by using a Bayesian model and dynamic thresholding to reduce false discoveries.

The paper introduces mvTCR, a multimodal generative model for integrating TCR and transcriptome data to improve analysis of single-cell immune profiling data.

The paper introduces NicheCompass, a graph deep learning method for characterizing cell niches in spatial omics data, showing improved performance in identifying and analyzing niches across multiple biological contexts.