Author

Saeedeh Mahmoodifar

University of Southern CaliforniaORCID 0009-0005-1279-5650Unclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

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Approach:statistical model· 1

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K. StuckeyiD· 1 shared Paul K. NewtoniD· 1 shared

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K. StuckeyORCID

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Systems BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 8, 2025

Gaming the cancer-immunity cycle by synchronizing the dose schedules

Saeedeh Mahmoodifar, K. Stuckey, Paul K. Newton

The paper introduces a mathematical model of the cancer-immunity cycle to optimize chemotherapy and immunotherapy dosing schedules by synchronizing them with the cycle's period, showing that optimized timing can improve efficacy with lower doses.

5 citations

statistical model

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