BioinformaticsbioRxivPreprint
AI-guided discovery for low-resource peptide engineering using evolutionary scale modeling
Leo Andrekson, Robin Rydbergh, Rocío Mercado, Michaela Wenzel
SCARSE is a machine learning framework that improves peptide engineering by combining ESM2 embeddings with Gaussian process regression, outperforming baselines in low-data regimes and enabling efficient active learning.
DOI 10.64898/2026.06.25.734678