Michaela Wenzel

SCARSE is a machine learning framework that improves peptide engineering by combining ESM2 embeddings with Gaussian process regression, outperforming baselines in low-data regimes and enabling efficient active learning.

This paper describes the development of a platinum-based antibiotic, Pt1, which shows potent antibacterial activity against resistant Staphylococcus aureus strains and demonstrates in vivo efficacy in a murine infection model.

This study identifies two independent mechanisms by which daptomycin exerts its antibacterial effects: cell wall synthesis inhibition and membrane depolarisation.

This paper demonstrates that membrane-domain-dissolving antibiotics can reverse β-lactam resistance in MRSA by dissolving membrane domains, as shown through multiple experimental methods.

This study identifies FtsZ and SepF as essential for Z-ring formation in Bacillus subtilis and discovers BraB as a new cell division regulator through gene deletion experiments.