Author

Xianci Zeng

University of Massachusetts AmherstORCID 0009-0005-3475-071XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Caryn L. HeldtiD· 1 shared Jonathan W. P. ZajaciD· 1 shared Praveen MuralikrishnaniD· 1 shared Sapna SarupriaiD· 1 shared Sarah L. PerryiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBiophysics

Caryn L. HeldtORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintJun 15, 2026

Protein-Solvent Shape Complementarity as a Unifying Principle in Excipient-Mediated Protein Thermal Stability

Jonathan W. P. Zajac, Praveen Muralikrishnan, Xianci Zeng…·Sapna Sarupria

The paper uses molecular dynamics simulations to identify a unifying mechanism for excipient-mediated protein thermal stability based on shape complementarity between proteins and solvents.

DOI 10.64898/2026.06.12.731979

protein structuremechanistic / dynamical model

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