Caryn L. Heldt

Protein-Solvent Shape Complementarity as a Unifying Principle in Excipient-Mediated Protein Thermal Stability

The paper uses molecular dynamics simulations to identify a unifying mechanism for excipient-mediated protein thermal stability based on shape complementarity between proteins and solvents.

A continuous viral vaccine biomanufacturing platform utilizing multiple bioreactor configurations

This paper presents a continuous biomanufacturing platform for virus-like particle vaccines using multiple bioreactor configurations, demonstrating stable production and scalability.

Cracking the Capsid Code: A Computationally-Feasible Approach for Investigating Virus-Excipient Interactions in Biologics Design

This paper introduces CapSACIN, a computational framework to study virus-excipient interactions, showing it effectively models PPV stability and excipient effects.