GenomicsbioRxivPreprint
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements
Yan Hu, Sai Ma, Vinay K. Kartha…·Jason Daniel Buenrostro
The paper introduces PRINT, a deep learning method to correct chromatin accessibility data and analyze DNA-protein interactions, revealing structural and functional changes in cis-regulatory elements during hematopoiesis and aging.