Author

Ajay S. Labade

Broad InstituteORCID 0000-0003-1348-8220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrew EarliD· 2 shared Fabiana M. DuarteiD· 2 shared Jason Daniel BuenrostroiD· 2 shared Rojesh ShresthaiD· 2 shared Ruochi ZhangiD· 2 shared Adwait Salvi· 1 shared Alia MelikiiD· 1 shared Amy J. WagersiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Andrew EarlORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 24, 2024

Expansion in situ genome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repression

Ajay S. Labade, Zachary Chiang, Caroline Comenho…·Jason Daniel Buenrostro

The paper introduces ExIGS, a method linking nuclear abnormalities to chromatin repression hotspots in progeria fibroblasts.

14 citations

humanDNA methylation

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GenomicsbioRxivPreprintMar 28, 2023

Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements

Yan Hu, Sai Ma, Vinay K. Kartha…·Jason Daniel Buenrostro

The paper introduces PRINT, a deep learning method to correct chromatin accessibility data and analyze DNA-protein interactions, revealing structural and functional changes in cis-regulatory elements during hematopoiesis and aging.

22 citations

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Molecular BiologybioRxivPreprintJul 2, 2019

Nup93 and CTCF co-modulate spatiotemporal dynamics and function of the HOXA gene cluster during differentiation

Ajay S. Labade, Adwait Salvi, Krishanpal Karmodiya, Kundan Sengupta

This study shows Nup93 and CTCF regulate HOXA gene dynamics during differentiation by modulating chromatin organization and gene expression.

4 citations

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