Author

Alyssa Lu Lee

Rutgers, The State University of New JerseyORCID 0009-0005-4407-6853Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 2 Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Approach:large language model· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Rohan MaddamsettiiD· 2 shared Arya Sharma· 1 shared Austin SeamanniD· 1 shared Clairie Zhao· 1 shared Gwendolyn Chung· 1 shared Sagar D. KhareiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

Rohan MaddamsettiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 4, 2026

HaloMPNN: retraining ProteinMPNN on halophilic proteomes for salt-tolerant enzyme design

Alyssa Lu Lee, Austin Seamann, Gwendolyn Chung…·Sagar D. Khare

This paper retrained ProteinMPNN on halophilic proteomes to design salt-tolerant enzymes, showing HaloMPNN shifts protein properties toward halophilic traits.

DOI 10.64898/2026.08.02.742362

protein sequencedeep learning

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJan 21, 2026

Zero-shot ecological annotation of microbial genomes with myLLannotator accelerates scientific discovery

Alyssa Lu Lee, Arya Sharma, Rohan Maddamsetti

myLLannotator uses a large language model to annotate microbial genomes, enabling rapid discovery of gene patterns in endosymbiotic bacteria.

DOI 10.64898/2026.01.18.700140

bacteria (other)whole-genome sequencing

𝕏 PostBluesky