Author

Chesney Melissinos

Cornell UniversityORCID 0009-0005-4443-8797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:database / resource· 2 Organism:plant (other)· 2 Research Focus:benchmarking· 1 Approach:large language model· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1

Frequent Co-Authors

Gaurav D. MogheiD· 2 shared Nathaniel S. S. SmithiD· 2 shared Xinyu YuaniD· 2 shared Crystal Grissom· 1 shared SAHAJ SATANIiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBioinformatics

Gaurav D. MogheORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 12, 2026

Systematic functional annotation of thousands of BAHD acyltransferases in plant genomes using Protein Language Model and phylogenomic tools

Nathaniel S. S. Smith, Xinyu Yuan, Chesney Melissinos…·Gaurav D. Moghe

The paper develops FuncZymeDB-BAHD and FuncPred tools to systematically annotate BAHD acyltransferase functions in plants using LLMs and phylogenomics, achieving high prediction accuracy and expanding existing databases.

DOI 10.64898/2026.06.09.730906

plant (other)protein sequence

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BioinformaticsBioinformaticsPeer-reviewedDec 20, 2024

FuncFetch: An LLM-assisted workflow enables mining thousands of enzyme-substrate interactions from published manuscripts

Nathaniel S. S. Smith, Xinyu Yuan, Chesney Melissinos, Gaurav D. Moghe

FuncFetch uses an LLM to mine enzyme-substrate interactions from manuscripts, achieving high precision and recall in extracting functional data.

24 citations

plant (other)large language model

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