GenomicsbioRxivPreprint
A Plasmid-Derived Machinery Drives Chromosomal Replication Initiation in the Colorectal Cancer-Associated Bacterium Fusobacterium nucleatum and Its Close Relatives
Sophie Pasek, Pierre Brézellec
The paper shows that Fusobacteriaceae bacteria use a plasmid-derived replication initiator protein, RPA, instead of the chromosomal dnaA gene, displacing the ancestral system.
DOI 10.64898/2026.10.08.757545