Johannes Wirtz

This study shows that genome architecture and gene-gene interactions influence the repeatability of polygenic adaptation in two copepod species with different chromosome numbers.

The paper models duplication-selection dynamics in gene families, showing that finite populations experience unbounded copy number growth unless counteracted by synergistic epistasis.

This paper introduces PIV models to estimate dispersal velocity of evolving lineages and shows improved accuracy in predicting pathogen spread using West Nile virus data.

The paper investigates the relationship between chromatin architecture and recombination landscapes in human and mouse, finding that GC-rich TADs correlate with increased recombination and specific protein binding.