Author

Kiran H. Kumar

University of MichiganORCID 0009-0005-5270-045XUnclaimed ORCID profile · follow to get notified of new preprints

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Biology Disciplines

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Research Focus:imputation· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:human· 1 Approach:matrix factorization· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Sebastian ZoellneriD· 2 shared Bárbara Sousa da MotaiD· 1 shared David ReichiD· 1 shared Simone RubinacciiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

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4 top collaborators · 4 mutual co-author links

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2 shared papersGenomics

Sebastian ZoellnerORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 28, 2026

Optimal Reference Panel Design in Ancient DNA Imputation from Coalescent Theory, Simulation, and Real Data Application with an Ancient Reference Panel

Bárbara Sousa da Mota, Kiran Kumar, David Reich, Sebastian Zoellner

This paper evaluates optimal reference panels for ancient DNA imputation using coalescent theory, simulations, and a real dataset, finding that including ancient samples improves imputation accuracy for rare variants.

DOI 10.64898/2026.04.27.721163

humanwhole-genome sequencing

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GenomicsThe American Journal of Human GeneticsPeer-reviewedMar 1, 2026

MetaGLIMPSE: Meta Imputation of Low Coverage Sequencing Data for Modern and Ancient Genomes

Kiran H. Kumar, Simone Rubinacci, Sebastian Zoellner

MetaGLIMPSE improves low coverage sequencing imputation by combining multiple reference panels, outperforming single-panel methods for modern and ancient DNA samples across various coverage and allele frequency ranges.

1 citation

whole-genome sequencingstatistical model

𝕏 PostBluesky