Detecting significantly recurrent genomic connections from simple and complex rearrangements in the cancer genome
Shu Zhang, Kiran H. Kumar, Ofer Shapira, Xiaotong Yao, Jeremiah A. Wala, Frank P. B. Dubois, Rose Meng Gold, James E. Haber, Andrew D. Cherniack, Marcin B. Imielinski, Simona Dalin, Rameen Beroukhim
This paper introduces two methods to detect recurrent genomic rearrangements in cancer genomes and identifies 80 simple and 29 complex rearrangements across 2,500 cancers.
bioRxiv · Oct 13, 2023 · PreprintGenomics