Author
Boston Children's HospitalORCID 0009-0005-6161-1459Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Diane D. Shao, Yifan Zhao, Joseph Brew…·Christopher A. Walsh
The paper investigates somatic copy number variants (CNVs) in human neurons across development, finding that perinatal elimination of neurons with aberrant genomes reduces CNV prevalence and targets dosage-sensitive genes.
Daniel A. Snellings, Kow Essuman, Benjamin Finander…·Christopher A. Walsh
The paper identifies pervasive somatic NF1 mutations in oligodendrocyte precursors in NF-1 patients, showing clonal selection and spatial bias, and links CDKN2A loss to tumor progression.
Xuyu Qian, Kyle Coleman, Shunzhou Jiang…·Christopher A. Walsh
The paper uses spatial single-cell analysis to uncover molecular and structural development of human fetal cortex, revealing early layer and area specification.