Kerlen T. Korbeld

The paper develops a computational method to deconvolve cell cycle-dependent protein dynamics from bulk proteomics data in budding yeast and identifies 563 proteins with such dynamics.

This study evaluates refolding metrics in protein design, showing they are limited by evolutionary information and structural flexibility, reducing their reliability for filtering design candidates.

BoostMut improves thermostability mutation prediction by automating analysis of molecular dynamics simulations and integrating biophysical features.