Robert T. Heussner

COEXIST integrates serial multiplexed tissue images at the single-cell level by combining molecular profiles with spatial information to improve profiling and platform validation.

The paper presents an image analysis pipeline for detecting circulating hybrid cells in immunofluorescence images with human-level accuracy using a β-VAE and SVM classifier.

The paper introduces a method to evaluate segmentation performance in multiplex tissue imaging without ground truth labels by comparing segmentations from an ensemble of models.