John Cappuccitti

This paper introduces a method to create scaffold-free hollow tissue constructs using anchored cell sheet engineering, enabling the formation of tubular and spherical structures with mechanical stability and biological function.

This paper develops engineered ECM fibers using Anchored Cell Sheet Engineering to treat volumetric muscle loss in rats, showing improved tissue regeneration and preservation compared to commercial ECM.

This study develops scaffold-free 3D in vitro models of muscular dystrophies using patient-specific cells, showing they closely mimic in vivo conditions and respond to therapeutic drugs.