BioinformaticsbioRxivPreprint
Identification of Therapeutic Gene Targets in Triple-Negative Breast Cancer: A Hybrid Approach Integrating Semidefinite Programming, Boolean Simulation, and Druggability Analysis
Sérgio Assunção Monteiro, Luis Alfredo Vidal de Carvalho, Fabrício Alves Barbosa da Silva
This paper identifies a promising therapeutic target pair for TNBC using a hybrid approach combining SDP, Boolean simulation, and druggability analysis, achieving higher druggability and lower complexity than prior methods.
DOI 10.1101/2025.11.05.686831